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PAUCOCEF (CEFTRIAXONE INJ 1G IM/IV)

₦ 250.00

Category: Injectable & I.V Fluids

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Brand Name: Rocephin

Generic Name: Ceftriaxone

Drug Class: Cephalosporins, 3rd Generation

WHAT IS CEFTRIAXONE AND HOW DOES IT WORK?

 

Ceftriaxone is used to treat a wide variety of bacterial infections. Ceftriaxone belongs to a class of drugs known as cephalosporin antibiotics. It works by stopping the growth of bacteria.

Ceftriaxone is not recommended for use in newborns with high blood bilirubin levels and premature infants due to increased risk of side effects. Ask the doctor or pharmacist for details.

Ceftriaxone may also be used before dental procedures in people with certain heart conditions (such as artificial heart valves) to help prevent serious infection of the heart (bacterial endocarditis).

Ceftriaxone is available under the following different brand names: Rocephin.

Dosages of Ceftriaxone:

Adult and Pediatric Dosage Forms and Strengths

Injectable solution

• 1 g/50 mL
• 2 g/50mL

Powder for injection

• 250 mg
• 500 mg
• 1 g
• 2 g
• 10 g (adult only)
• 100 g (adult only)

Dosage Considerations – Should be Given as Follows:

Intra-abdominal Infections

• Complicated, mild-to-moderate, community acquired: 1-2 g/day intravenously (IV) in single daily dose or divided every 12 hours for 4-7 days, in combination with metronidazole

Acute Bacterial Otitis Media

• Adult: 50 mg/kg intramuscularly (IM) once
• Persistent or treatment failures: 50 mg/kg intravenously/intramuscularly (IV/IM) for 3 days
• Pediatric: 50 mg/kg IM in single dose; not to exceed 1 g

Pelvic Inflammatory Disease

• 250 mg intramuscularly (IM) as single dose with doxycycline, with or without metonidazole for 14 days

Septic/toxic Shock (Off-label)

• 2 g intravenously (IV) once daily; with clindamycin for toxic shock

Skin and Soft Necrotizing Infection (Off-label)

• Due to Aeromonas hydrophilia: 1-2 g intravenously (IV) once/day in combination with doxycycline
• Due to Vibrio vulnificus; 1 g IV once/day in combination with doxycycline
• Continue treatment until further debridement not necessary, clinical improvement observed, and patient is afebrile for 48-72 hours
• Children over 12 years: 1-2 g/day intravenously/intramuscularly (IV/IM) in single daily dose or divided every 12 hours for 7-14 days, depending on type and severity of infection

Severe Acute Bacterial Rhinosinusitis (Off-label)

• Infection requiring hospitalization: 1-2 g intravenously (IV) every 12-24 hours for 5-7 days

Prosthetic Joint Infection

• 2 g intravenously (IV) every 24 hours for 2-6 weeks; continue treatment until clinical improvement observed and patient is afebrile for 48-72 hours

Meningitis

• Adult: 2 g intravenously (IV) every 12 hours for 7-14 days
• Pediatric: 100 mg/kg/day intravenously/intramuscularly (IV/IM) in single daily dose or divided every 12 hours for 7-14 days; not to exceed 4 g/day
• Serious Infections Other Than Meningitis, Pediatric
• 50-75 mg/kg/day intravenously/intramuscularly (IV/IM) divided every 12 hours for 7-14 days

Acute Uncomplicated Pyelonephritis

• 1-2 g intravenously (IV) once/day

Surgical Prophylaxis

Prophylaxis of surgical infection

• 1 g intravenously (IV) 0.5-2 hours before procedure